Genome‐Wide Association Studies of Cognitive and Motor Progression in Parkinson's Disease
Movement Disorders2020Vol. 36(2), pp. 424–433
Citations Over TimeTop 10% of 2020 papers
Manuela Tan, Michael Lawton, Edwin Jabbari, Regina H. Reynolds, Hirotaka Iwaki, Cornelis Blauwendraat, Sofia Kanavou, Miriam I. Pollard, Leon Hubbard, Naveed Malek, Katherine A. Grosset, Sarah Marrinan, Nin Bajaj, Roger A. Barker, David J. Burn, Catherine Bresner, Thomas Foltynie, Nicholas Wood, Caroline H. Williams‐Gray, John Hardy, Michael A. Nalls, Andrew Singleton, Nigel Williams, Yoav Ben‐Shlomo, Michele T.M. Hu, Donald G. Grosset, Maryam Shoai, Huw R. Morris
Abstract
We provide early evidence that this new method in PD improves measurement of symptom progression. We show that the APOE ε4 allele drives progressive cognitive impairment in PD. Replication of this method and results in independent cohorts are needed. © 2020 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
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