A Monte Carlo approach to the microdosimetric kinetic model to account for dose rate time structure effects in ion beam therapy with application in treatment planning simulations
Medical Physics2017Vol. 44(4), pp. 1577–1589
Citations Over TimeTop 10% of 2017 papers
L Manganaro, G. V. Russo, R. Cirio, F Dalmasso, S. Giordanengo, V. Monaco, S. Muraro, R. Sacchi, A. Vignati, A. Attili
Abstract
The present study provides a framework for exploiting the temporal effects of dose delivery. The results show the possibility of optimizing the treatment outcomes accounting for the correlation between the specific dose rate time structure and the spatial characteristic of the LET distribution, depending on the ion type used.
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