Feasibility study of using fall‐off gradients of early and late PET scans for proton range verification
Medical Physics2017Vol. 44(5), pp. 1734–1746
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Jongmin Cho, K. S. Grogg, Chul Hee Min, Xuping Zhu, Harald Paganetti, Hyun Cheol Lee, Georges El Fakhri
Abstract
The subtracted PET signal gradient peaks and the proton ranges for water-gel and tissue-gel show distance off-sets of 4 to 5 mm. This off-set may potentially be used for proton range verification using only the PET measured data without Monte Carlo simulations. More studies are necessary to overcome various limitations, such as perfusion-driven washout, for the feasibility of this technique in living patients.
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