Optimization of treatment isocenter location in single‐isocenter LINAC‐based stereotactic radiosurgery for management of multiple brain metastases
Medical Physics2021Vol. 48(12), pp. 7632–7640
Citations Over TimeTop 12% of 2021 papers
Abstract
The proposed framework provides an effective approach to determine the optimal isocenter of single-isocenter LINAC-based SRS plans for multiple brain metastases. The implementation of the optimal isocenter results in SRS plans with consistently higher target coverage despite potential rotational uncertainties, and therefore significantly improves SRS plan robustness against random rotational uncertainties.
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