The population percentile allowance method for determining systematic spatial error tolerances for temporary intensity modulated brachytherapy
Medical Physics2023Vol. 50(10), pp. 6469–6478
Citations Over Time
Karolyn M. Hopfensperger, Quentin E. Adams, Yusung Kim, Xiaodong Wu, Weiyu Xu, Kaustubh Patwardhan, Ryan T. Flynn
Abstract
The PPA method was formalized to determine the temporary IMBT spatial uncertainty tolerances that would be expected to result in an allowed percentage of a population of patients receiving relative dose-volume errors above a defined percentage. Multi-shield, helical 169 Yb-based RSBT for cervical cancer was evaluated and tolerances determined, which, if applied on each treatment fraction, would represent an extreme situation. The PPA method is applicable to a variety of temporary IMBT approaches and can be used to rigorously determine the design parameters for the delivery systems such as mechanical driver motor accuracy, shield angle backlash, applicator rotation, and applicator fixation stability.
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