The LET trilemma: Conflicts between robust target coverage, uniform dose, and dose‐averaged LET in carbon therapy
Medical Physics2023Vol. 50(12), pp. 7338–7348
Citations Over TimeTop 10% of 2023 papers
Abstract
There is an inherent conflict between range uncertainty robustness and high LETd in the target, which is aggravated with increasing target size. For large tumors, it is possible to simultaneously achieve two of the three qualities range robustness, uniform dose, and high LETd in the target.
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