Biological‐equivalent‐dose‐based integrated optimization framework for fast‐energy‐switching Bragg peak FLASH‐RT using single‐beam‐per‐fraction
Medical Physics2024Vol. 51(9), pp. 6292–6304
Citations Over TimeTop 10% of 2024 papers
Y. Zeng, Heng Li, Qi Zhang, Wei Wang, Xu Liu, Bin Qin, Bo Pang, Muyu Liu, Kunyu Yang, Hong Quan, Yu Chang, Zhiyong Yang
Abstract
The EQD2-IOF can automatically optimize SBPF FLASH-RT plans to achieve optimal sparing of normal tissues. With an energy switching time of 27 ms, the loss of fractionate repairing using SBPF schedules in high-dose regions can be compensated for by the FLASH effect. However, when an energy switching time of 500 ms is utilized, the SBPF schedule needs careful consideration, as the FLASH effect diminishes with longer irradiation time.
Related Papers
- → High LET-Like Radiation Tracks at the Distal Side of Accelerated Proton Bragg Peak(2021)20 cited
- → Biological Dose Estimation Model for Proton Beam Therapy(2015)8 cited
- → SU‐FF‐T‐411: Boundary Study of Bragg Peak Shift and Bragg Peak Degradation in Proton Dose Calculation(2009)1 cited
- Reflections on the Design of Flash Courseware(2005)
- → Photo Editing in Photoshop and Flash(2006)