Optimizing spot intensity with lower bound constraints for IMPT: Exposing shortcomings and introducing an enhanced strategy
Medical Physics2024Vol. 51(10), pp. 7523–7544
Citations Over Time
Dong Han, Jingdong Tong, Yu Yang, Hongcheng Liu, Xiaoying Liang, Sridhar Yaddanapudi, Chunjoo Park, Jun Tan, Keith M. Furutani, Chris Beltran, Jiahong Lu
Abstract
Our Two-Stage MILP strategy signifies a significant advancement in IMPT treatment planning. By incorporating LB constraints directly into the optimization process, it achieves superior plan quality and deliverability compared to current methods. This approach is particularly advantageous in clinical settings requiring minimum spot number and high MU LB constraints, offering the potential for improved patient outcomes through more precise and efficient radiation therapy plans.
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