Detection of hepatic oxidative DNA damage in patients with hepatoblastoma and children with non‐neoplastic disease
Medical and Pediatric Oncology2001Vol. 37(6), pp. 505–510
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Abstract
These results suggest that the cause of oxidative DNA damage in patients with hepatoblastoma may be different from the cause, extensive parenchymal damage to the liver, in children with non-neoplastic disease, but the 8-OHdG formation is not specific to hepatoblastoma patients of low birth weight. Further studies to elucidate the true reason for the high incidence of hepatoblastoma in children of low birth weight are necessary.
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