Time‐resolved contrast‐enhanced imaging with isotropic resolution and broad coverage using an undersampled 3D projection trajectory

Citations Over TimeTop 1% of 2002 papers

Abstract

Time-resolved contrast-enhanced 3D MR angiography (MRA) methods have gained in popularity but are still limited by the tradeoff between spatial and temporal resolution. A method is presented that greatly reduces this tradeoff by employing undersampled 3D projection reconstruction trajectories. The variable density k-space sampling intrinsic to this sequence is combined with temporal k-space interpolation to provide time frames as short as 4 s. This time resolution reduces the need for exact contrast timing while also providing dynamic information. Spatial resolution is determined primarily by the projection readout resolution and is thus isotropic across the FOV, which is also isotropic. Although undersampling the outer regions of k-space introduces aliased energy into the image, which may compromise resolution, this is not a limiting factor in high-contrast applications such as MRA. Results from phantom and volunteer studies are presented demonstrating isotropic resolution, broad coverage with an isotropic field of view (FOV), minimal projection reconstruction artifacts, and temporal information. In one application, a single breath-hold exam covering the entire pulmonary vasculature generates high-resolution, isotropic imaging volumes depicting the bolus passage.

Related Papers

• → An empirical comparison of repetitive undersampling techniques(2009)47 cited
• → Detecting undersampling in surface reconstruction(2001)109 cited
• → Undersampling patterns in k-space for compressed sensing MRI using two-dimensional Cartesian sampling(2018)15 cited
• → Combined compressed sensing and parallel mri compared for uniform and random cartesian undersampling of K-space(2011)8 cited
• → Applying undersampling to the nuclear magnetic resonance signal(2002)2 cited