Effects of dietary protein to carbohydrate balance on energy intake, fat storage, and heat production in mice
Obesity2013Vol. 21(1), pp. 85–92
Citations Over TimeTop 10% of 2013 papers
Xin Huang, Dale Hancock, Alison K. Gosby, Aisling C. McMahon, Samantha M. Solon‐Biet, David G. Le Couteur, Arthur D. Conigrave, David Raubenheimer, Stephen J. Simpson
Abstract
Low-protein diets induced sustained hyperphagia and a generalized expansion of fat stores. Increased body surface temperature on low P:C diets was consistent with diet-induced thermogenesis (DIT) as a means to dissipate excess ingested energy on such diets, although this was not sufficient to prevent development of increased adiposity. Whether BAT was involved in DIT is not clear. Increased BAT mass on low P:C diets might suggest so, but patterns of thermogenic gene expression do not support a role for BAT in DIT, although they might reflect failure of thermogenic function with prolonged exposure to a low P:C diet.
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