Circulating regulatory T cells are reduced in obesity and may identify subjects at increased metabolic and cardiovascular risk
Obesity2013Vol. 21(3), pp. 461–468
Citations Over TimeTop 10% of 2013 papers
Nana‐Maria Wagner, Gunnar Brandhorst, Frauke Czepluch, Mareike Lankeit, Christoph Eberle, Sebastian Herzberg, Vivien Faustin, J. Riggert, Michael Oellerich, Gerd Hasenfuß, Stavros Konstantinides, Katrin Schäfer
Abstract
Our findings thus reveal an association between circulating Treg cells and measures of adiposity, inflammation, and glucose intolerance. Although further prospective studies are needed, we present data suggesting that the determination of Treg cells might be useful to identify obese subjects at increased risk of developing cardiovascular and/or metabolic complications.
Related Papers
- → Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells(2006)1,490 cited
- → Incomplete Depletion and Rapid Regeneration of Foxp3+ Regulatory T Cells Following Anti-CD25 Treatment in Malaria-Infected Mice(2007)150 cited
- → Expression of IL-7 receptor in human peripheral regulatory T cells(2012)16 cited
- [The decreased proportion of CD4+CD25+FOXP3+ regulatory T cells in peripheral blood of children with juvenile idiopathic arthritis and its negative correlation with cytokine level].(2022)
- → 414.9: Shared Transcriptional Trajectory of Tissue Tregs Between Tolerant-Grafts and Lymphoid Organs in Transplant Tolerance(2022)