Obesity‐related dysregulation of the Tryptophan–Kynurenine metabolism: Role of age and parameters of the metabolic syndrome
Obesity2013Vol. 22(1), pp. 195–201
Citations Over TimeTop 10% of 2013 papers
Harald Mangge, Kelli L. Summers, Andreas Meinitzer, Sieglinde Zelzer, Gunter Almer, Ruth Prassl, W. Schnedl, Eva Z. Reininghaus, Katharina Paulmichl, Daniel Weghuber, Dietmar Fuchs
Abstract
TRP metabolism and obesity-related immune mediated inflammation differs markedly between juveniles and adults. While childhood obesity seems to be dominated by a Th2-driven activation, an accelerated production of Th1-type cytokines may pave the way for later atherosclerotic endpoints.
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