Functional redundancy between glucocorticoid and mineralocorticoid receptors in mature corticotropin‐releasing hormone neurons protects from obesity
Obesity2024Vol. 32(10), pp. 1885–1896
Citations Over TimeTop 22% of 2024 papers
Yu Liu, Dongfa Lin, Syeda Sadia Najam, Shangyuan Huang, Muyi Song, Chaweewan Sirakawin, Catherine Zhao, Haixia Jiang, Witold Konopka, Stephan Herzig, Ilya A. Vinnikov
Abstract
Our data demonstrate the functional redundancy of GRs and MRs in CRH neurons to maintain energy homeostasis and prevent obesity. Simultaneous targeting of both receptors might represent an unprecedented approach to counteract obesity.
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