Dual Enzyme‐Triggered Controlled Release on Capped Nanometric Silica Mesoporous Supports
ChemistryOpen2012Vol. 1(1), pp. 17–20
Citations Over TimeTop 10% of 2012 papers
Alessandro Agostini, Laura Mondragón, Carmen Coll, Elena Aznar, M. Dolores Marcos, Ramón Martínez‐Máñez, Félix Sancenón, Juán Soto, Enríque Pérez‐Payá, Pedro Amorós
Abstract
Please release me: Mesoporous silica nanoparticles capped with bulky organic moieties containing amide and urea linkages were able to release their cargo upon addition of amidase and urease. Amidase induced an immediate, yet not complete, release of the cargo. On the other hand, urease allowed a near total cargo release that was delayed in time (see graph).
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