An Artificial Molecular Transporter
Citations Over TimeTop 12% of 2015 papers
Abstract
The transport of substrates is one of the main tasks of biomolecular machines in living organisms. We report a synthetic small-molecule system designed to catch, displace, and release molecular cargo in solution under external control. The system consists of a bistable rotaxane that behaves as an acid-base controlled molecular shuttle, whose ring component bears a tether ending with a nitrile group. The latter can be coordinated to a ruthenium complex that acts as the load, and dissociated upon irradiation with visible light. The cargo loading/unloading and ring transfer/return processes are reversible and can be controlled independently. The robust coordination bond ensures that the cargo remains attached to the device while the transport takes place.
Related Papers
- → Transition metal-complexed catenanes and rotaxanes as molecular machine prototypes(2005)159 cited
- → A kinetically controlled molecular switch based on bistable [2]rotaxane(2001)88 cited
- → Templated Synthesis of a Rotaxane with a [Ru(diimine)3]2+ Core(2003)54 cited
- → Rotaxane-based molecular machines operated by photoinduced electron transfer(2005)13 cited
- Study on Bistable Devices Based on Rotaxane Monolayer Molecules(2008)