Intensive chemotherapy followed by consolidative myeloablative chemotherapy with autologous hematopoietic cell rescue (AuHCR) in young children with newly diagnosed supratentorial primitive neuroectodermal tumors (sPNETs): Report of the Head Start I and II experience
Pediatric Blood & Cancer2007Vol. 50(2), pp. 312–318
Citations Over TimeTop 10% of 2007 papers
Jason Fangusaro, Jonathan L. Finlay, Richard Sposto, Lingyun Ji, Monirath Saly, Stergios Zacharoulis, Shahab Asgharzadeh, Minnie Abromowitch, Randal Olshefski, Steven Halpern, Ronald L. Dubowy, Melanie Comito, Blanca Diez, Stewart J. Kellie, Juliette Hukin, Marc K. Rosenblum, Ira J. Dunkel, Douglas C. Miller, Jeffrey C. Allen, Sharon L. Gardner
Abstract
ICHT followed by AuHCR in young patients with newly diagnosed sPNET appears to not only provide an improved EFS and OS for patients who typically have a poor prognosis, but also it successfully permitted deferral and elimination of radiation therapy in a significant proportion of patients.
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