Impact of chemotherapy on disseminated low‐grade glioma in children and adolescents: Report from the HIT‐LGG 1996 trial
Pediatric Blood & Cancer2011Vol. 56(7), pp. 1046–1054
Citations Over TimeTop 13% of 2011 papers
Stephan von Hornstein, Rolf‐D. Kortmann, Torsten Pietsch, Angela Emser, Monika Warmuth‐Metz, Niels Soerensen, Ronald Straeter, Norbert Graf, Barbara Thieme, Astrid Gnekow
Abstract
Complete MRI scan should be a standard diagnostic procedure in young children with hypothalamic-chiasmatic tumors especially if presenting with diencephalic syndrome. Dissemination in childhood LGG relates to impaired PFS. CT delays progression for responders. Multicenter studies have to evaluate the efficacy of extended treatment strategies in DLGG to improve outcome.
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