The UK Experience of a Treatment Strategy for Pediatric Metastatic Medulloblastoma Comprising Intensive Induction Chemotherapy, Hyperfractionated Accelerated Radiotherapy and Response Directed High Dose Myeloablative Chemotherapy or Maintenance Chemothera
Pediatric Blood & Cancer2015Vol. 62(12), pp. 2132–2139
Citations Over TimeTop 16% of 2015 papers
Sindu Vivekanandan, Richard Breene, Ramya Ramanujachar, Heidi Traunecker, Barry Pizer, Mark N. Gaze, Frank Saran, Nicky Thorp, Martin English, Kate Wheeler, Antony Michalski, David Walker, D.J. Saunders, Fiona Cowie, Alison Cameron, Susan Picton, Deepak Parashar, Gail Horan, M.V. Williams
Abstract
Within the limits of statistical significance, we did not replicate the improved survival results reported in the original series. The reasons include differences in patient sub-groups and protocol administration. International randomized phase III studies are needed.
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