Feasibility and clinical integration of molecular profiling for target identification in pediatric solid tumors
Pediatric Blood & Cancer2016Vol. 64(6)
Citations Over TimeTop 10% of 2016 papers
Thomas Pincez, Nathalie Clément, Eve Lapouble, Gaëlle Pierron, Maud Kamal, Ivan Bièche, Virginie Bernard, Paul Fréneaux, J Michon, Daniel Orbach, Isabelle Aerts, Hélène Pacquement, Franck Bourdeaut, Irène Jiménez, Estelle Thébaud, Caroline Oudot, Cécile Verite, Sophie Taque, Cormac Owens, François Doz, Christophe Le Tourneau, Olivier Delattre, Gudrun Schleiermacher
Abstract
Pediatric molecular profiling is feasible, with more than a third of patients being eligible to receive targeted therapy, yet only a small proportion were treated with these therapies. Analysis at diagnosis may be useful for children with very poor prognosis tumsors.
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