Hepatic sinusoidal obstruction syndrome during maintenance therapy of childhood acute lymphoblastic leukemia is associated with continuous asparaginase therapy and mercaptopurine metabolites
Pediatric Blood & Cancer2017Vol. 64(9)
Citations Over TimeTop 10% of 2017 papers
Linea Natalie Toksvang, Silvia De Pietri, Stine Nygaard Nielsen, Jacob Nersting, Birgitte Klug Albertsen, Peder Skov Wehner, Steen Rosthøj, Päivi M. Lähteenmäki, Daniel Nilsson, Tove A. Nystad, Kathrine Grell, Thomas Leth Frandsen, Kjeld Schmiegelow
Abstract
PEG-asparaginase increases cytotoxic 6MP metabolite levels and risk of SOS, potentially interacting with other chemotherapy pulses.
Related Papers
- → Nutritional therapy versus 6-mercaptopurine as maintenance therapy in patients with Crohn's disease(2012)73 cited
- → Monitoring asparaginase activity to improve the management of patients with acute lymphoblastic leukemia: Experience in one center(2024)2 cited
- → Use of PEG-asparaginase in newly diagnosed adults with standard-risk acute lymphoblastic leukemia compared with E. coli-asparaginase: a retrospective single-center study(2016)9 cited
- → Comparison of prednisolone, vincristine, methotrexate and 6-mercaptopurine vs. 6-mercaptopurine and prednisone maintenance therapy in childhood acute leukemia: A southwest oncology group study(1980)8 cited
- → A Simplistic Individualization Method for 6-Mercaptopurine in Acute Lymphoblastic Leukemia Children(2007)3 cited