Improvement of overall survival in the Collaborative Wilms Tumour Africa Project
Pediatric Blood & Cancer2020Vol. 67(9), pp. e28383–e28383
Citations Over TimeTop 12% of 2020 papers
George Chagaluka, Vivian Paintsil, Lorna Renner, Janna Weijers, Inam Chitsike, Eric Borgstein, Steve Kamiza, Glenn Mbah Afungchwi, Francine Kouya, Peter Hesseling, Elizabeth Molyneux, Trijn Israëls
Abstract
This collaborative implementation of an adapted WT treatment guideline, using relatively simple and low-cost interventions, was feasible. Two-year EFS was almost 50%. In addition, a significant decrease in treatment abandonment and an increase in survival at the end of treatment were observed compared to a pre-implementation cohort. Future work should focus on decreasing deaths during treatment and will include enhancing supportive care.
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