Prenatal cytogenetic assessment and inv(2)(p11.2q13)
Prenatal Diagnosis2006Vol. 26(9), pp. 810–813
Citations Over TimeTop 19% of 2006 papers
Meaghan Hysert, Hélène Bruyèrè, Gilbert B. Côté, Angelika J. Dawson, J.-A. Dolling, Raouf Fetni, Monica Hrynchak, Josée N. Lavoie, Jean McGowan‐Jordan, Frédérique Tihy, Alessandra M.V. Duncan
Abstract
Our study, and data from the literature, suggests that most cases of inv(2)(p11.2q13) have been stably inherited, that de novo cases of inv(2) are rare and that both inherited and de novo forms are without phenotypic or developmental consequences. We suggest that parental karyotyping for cases of inv(2) is not useful in counselling as it may generate unnecessary parental anxiety over a chromosomal finding that is likely innocuous.
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