Determination of the genetic status of cleavage‐stage human embryos by microsatellite marker analysis following multiple displacement amplification
Prenatal Diagnosis2007Vol. 27(3), pp. 206–215
Citations Over TimeTop 10% of 2007 papers
Abstract
Abnormalities in human embryos may be present in only a single cell, leading to potentially false abnormal results at pre-implantation genetic diagnosis. ADO associated with MDA reduces the efficacy of this approach for detection of aneuploidy. Statistical analysis showed that, for ADO of 28%, seven informative markers would be required to give 95% confidence of detecting trisomic embryos.
Related Papers
- → Preimplantation genetic screening reveals a high incidence of aneuploidy and mosaicism in embryos from young women undergoing IVF(2005)307 cited
- → Increased blastomere number in cleavage-stage embryos is associated with higher aneuploidy(2014)47 cited
- → MOLECULAR MARKERS IN TROPICAL AND SUBTROPICAL HORTICULTURE(1998)3 cited
- → Does embryo blastomere symmetry predict aneuploidies?(2009)
- → The assosiation between preimplantation embryo morphology and the incidence of chromosome aneuploidy(2008)