Biological explanations for discordant noninvasive prenatal test results: Preliminary data and lessons learned
Prenatal Diagnosis2018Vol. 38(6), pp. 445–458
Citations Over TimeTop 10% of 2018 papers
Louise Wilkins‐Haug, Chengsheng Zhang, Eliza Cerveira, Mallory Ryan, Adam Mil-Homens, Qihui Zhu, Honey V. Reddi, Charles Lee, Diana W. Bianchi
Abstract
Understanding the biology behind cfDNA-fetal karyotype discordancy is useful for follow-up clinical care. Our study suggests that most cases could be resolved by using a trio biospecimen protocol and parental involvement. To improve accuracy, additional sequencing of biospecimens will be required.
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