Slower processing speed after treatment for pediatric brain tumor and acute lymphoblastic leukemia
Psycho-Oncology2013Vol. 22(9), pp. 1979–1986
Citations Over TimeTop 10% of 2013 papers
Lisa S. Kahalley, Heather M. Conklin, Vida L. Tyc, Melissa M. Hudson, Stephanie J. Wilson, Shengjie Wu, Xiaoping Xiong, Pamela S. Hinds
Abstract
Many pediatric BT and ALL survivors exhibit slower processing speed than expected for age, whereas general reasoning ability remains largely intact. Risk factors associated with larger EIQ-PSI discrepancies include the following: BT diagnosis, craniospinal irradiation (BT only), male gender, and younger age at diagnosis (ALL only). Grade retention was frequent and associated with lower EIQ scores (both groups) and PSI scores (ALL only). Describing post-treatment cognitive declines using global measures of intellectual ability may underestimate dysfunction or fail to isolate specific underlying deficits contributing to impairment.
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