Return of FEV1 after pulmonary exacerbation in children with cystic fibrosis
Pediatric Pulmonology2010Vol. 45(2), pp. 127–134
Citations Over TimeTop 10% of 2010 papers
Don B. Sanders, Lucas R. Hoffman, Julia Emerson, Ronald L. Gibson, Margaret Rosenfeld, Gregory J. Redding, Christopher H. Goss
Abstract
Approximately one in four patients with CF failed to recover to baseline lung function after a pulmonary exacerbation despite treatment with intravenous antibiotics. Failure to recover to baseline was associated with the degree of decline in FEV(1) that had occurred prior to hospital admission, suggesting opportunities for earlier intervention to improve lung function outcomes. Additional studies are needed to determine how the failure to recover to baseline affects subsequent FEV(1) decline.
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