Pulmonary exacerbations are associated with subsequent FEV1 decline in both adults and children with cystic fibrosis
Pediatric Pulmonology2010Vol. 46(4), pp. 393–400
Citations Over TimeTop 10% of 2010 papers
Abstract
There is a strong association between the frequency of pulmonary exacerbations and subsequent decline in pulmonary function. In adults, having 3+ exacerbations, and among children, having any exacerbations is associated with a greater rate of decline in the ensuing 3 years. Improved prevention, identification, and treatment of pulmonary exacerbations are likely to have long-term benefits for patients with CF, especially children.
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