Risk factors for lung function decline in a large cohort of young cystic fibrosis patients
Pediatric Pulmonology2015Vol. 50(8), pp. 763–770
Citations Over TimeTop 10% of 2015 papers
Jonathan D. Cogen, Julia Emerson, Don B. Sanders, Clement L. Ren, Michael S. Schechter, Ronald L. Gibson, Wayne J. Morgan, Margaret Rosenfeld, for the EPIC Study Group
Abstract
We have identified a range of risk factors for FEV1 decline in a large cohort of young, CF patients who were Pa negative at enrollment, including novel as well as previously identified characteristics. These results could inform the design of a clinical trial in which rate of FEV1 decline is the primary endpoint and identify high-risk groups that may benefit from closer monitoring.
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