The heterogeneity of viral bronchiolitis: A lack of universal consensus definitions
Citations Over TimeTop 10% of 2017 papers
Abstract
Viral bronchiolitis is one of the most common hospital presentations in infancy and as such represents a major healthcare burden worldwide. However despite this, there are currently no effective targeted therapies nor can those infants at highest risk for developing severe disease or subsequent respiratory morbidity be predicted on initial hospital presentation. Current definitions of bronchiolitis in the published literature vary significantly in terms of the age range at presentation, specific clinical symptoms, causative virus, and the inclusion or exclusion of infants with previous presentations and/or various comorbidities. In this review, we highlight how this heterogeneity among definitions contributes to a lack of clarity on this condition and its likely multiple endotypes. We argue that without a new universal consensus definition or sets of definitions, progress into bronchiolitis will continue to be stalled.
Related Papers
- → And now for something completely different: from 2019-nCoV and COVID-19 to 2020-nMan(2020)27 cited
- → What if the worst consequences of COVID-19 concerned non-COVID patients?(2020)22 cited
- The Covid‐19 Pandemic Highlights Key Roles for Economists La pandémie de Covid‐19 met en évidence les rôles importants des économistes Die Covid‐19‐Pandemie unterstreicht die Schlüsselrolle von Ökonominnen und Ökonomen(2020)
- → Pediatricians Face Challenges in Diagnosing Post-COVID-19 Conditions (Long COVID)(2023)