Montelukast reverses airway remodeling in actively sensitized young mice
Pediatric Pulmonology2018Vol. 53(6), pp. 701–709
Citations Over Time
Stéphane Debelleix, Valerie Siao-Him-Fa, Hugues Bégueret, Patrick Berger, А. В. Камаев, Olga Ousova, Roger Marthan, Michaël Fayon
Abstract
We provide thus evidence for a greater degree of AR after allergenic sensitization and challenge in younger mice versus adults. This study provides proof of concept that airway remodeling can be prevented and reversed in this case by anti-asthmatic drug Montelukast in this model.
Related Papers
- → Bronchial hyperresponsiveness to methacholine/AMP and the bronchodilator response in asthmatic children(2010)16 cited
- → Role of L‐arginine in the deficiency of nitric oxide and airway hyperreactivity after the allergen‐induced early asthmatic reaction in guinea‐pigs(1999)58 cited
- → Reactive dye induced occupational asthma without nonspecific bronchial hyperreactivity(1990)3 cited
- Effect of budesonide on bronchial hyperresponsiveness and pulmonary function in patients with mild to moderate asthma.(1994)
- Bronchial hyperresponsiveness to methacholine in relation to asthma control - Results from the MIDAS study(2013)