Improved protein extraction and protein identification from archival formalin‐fixed paraffin‐embedded human aortas
PROTEOMICS - CLINICAL APPLICATIONS2013Vol. 7(3-4), pp. 217–224
Citations Over TimeTop 10% of 2013 papers
Zongming Fu, Kun Yan, Avraham Rosenberg, Zhicheng Jin, Barbara J. Crain, Grace Athas, Richard S. Vander Heide, Timothy D. Howard, Allen D. Everett, David M. Herrington, Jennifer E. Van Eyk
Abstract
Combination of heat and high pressure is an effective method to extract proteins from FFPE aorta for downstream proteomics. This method opens the possibility for use of archival and often rare FFPE aortas and possibly other tissues available to proteomics for biomarker discovery and quantification.
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