CSF profiling of the human brain enriched proteome reveals associations of neuromodulin and neurogranin to Alzheimer's disease
PROTEOMICS - CLINICAL APPLICATIONS2016Vol. 10(12), pp. 1242–1253
Citations Over TimeTop 10% of 2016 papers
Julia Remnestål, David Just, Nicholas Mitsios, Claudia Fredolini, Jan Mulder, Jochen M. Schwenk, Mathias Uhlén, Kim Kultima, Martin Ingelsson, Lena Kilander, Lars Lannfelt, Per Svenningsson, Bengt Nellgård, Henrik Zetterberg, Kaj Blennow, Peter Nilsson, Anna Månberg
Abstract
These findings indicate that analyzing the brain-enriched proteins in CSF is of particular interest to increase the understanding of the CSF proteome and its relation to neurodegenerative disorders. In addition, this study lends support to the notion that measurements of these synaptic proteins could potentially be of great relevance in future diagnostic tests for AD.
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