Simulation of DNA damage using Geant4‐DNA: an overview of the “molecularDNA” example application
Precision Radiation Oncology2023Vol. 7(1), pp. 4–14
Citations Over TimeTop 10% of 2023 papers
Konstantinos Chatzipapas, Ngoc Hoang Tran, M. Dordevic, Sara Zivkovic, Sara A. Zein, Wook‐Geun Shin, D. Sakata, Nathanael Lampe, Jeremy M. C. Brown, Aleksandra Ristic‐Fira, Ivan Petrović, Ioanna Kyriakou, Dimitris Emfietzoglou, Susanna Guatelli, S. Incerti
Abstract
Simulation data in terms of single-strand break and double-strand break yields were produced using each of the available geometries. The results were compared with the literature, to validate the example, producing less than 5% difference in all cases. Conclusion: "molecularDNA" is a prototype tool that can be applied in a wide variety of radiobiology studies, providing the scientific community with an open-access base for DNA damage quantification calculations. New DNA and cell geometries for the "molecularDNA" example will be included in future versions of Geant4-DNA.
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