Differential expression of interleukin‐15, a pro‐inflammatory cytokine and T‐cell growth factor, and its receptor in human prostate
The Prostate2001Vol. 49(4), pp. 251–262
Citations Over TimeTop 24% of 2001 papers
Alessandra Handisurya, Georg Steiner, Ursula Stix, Rupert Ecker, Sabine Pfaffeneder‐Mantai, Dina Langer, Gero Kramer, Nima Memaran, Michael Marberger
Abstract
Overexpression of IL-15 and IL-15Ralpha-chain in BPH and massive proliferation of BPH-T-lymphocytes induced by IL-15 suggest a role for IL-15 in prostatic inflammation. Since IFN-gamma, a T-lymphocyte product, stimulates prostatic IL-15 production; chronic inflammation might be triggered by this paracrine loop.
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