Genome‐wide scan for prostate cancer susceptibility genes using families from the University of Michigan prostate cancer genetics project finds evidence for linkage on chromosome 17 near BRCA1
The Prostate2003Vol. 57(4), pp. 326–334
Citations Over TimeTop 10% of 2003 papers
Ethan M. Lange, Elizabeth M. Gillanders, Cralen Davis, W. Mark Brown, Joel K. Campbell, MaryPat Jones, Derek Gildea, Erica L. Riedesel, Julie Albertus, Diana Freas‐Lutz, Carol Markey, Veda N. Giri, Jennifer Beebe Dimmer, James E. Montie, Jeffrey M. Trent, Kathleen A. Cooney
Abstract
Genome-wide analysis of a large set of prostate cancer families indicates new areas of the genome that may harbor prostate cancer susceptibility genes. Specifically, our linkage results suggest that there is a prostate cancer susceptibility gene on chromosome 17 that is independent of ELAC2. Further research including combined analyses of independent genome-wide scan data may clarify the most important regions for future investigation.
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