Pathological features of prostate cancer detected on initial and repeat prostate biopsy: Results of the prospective European prostate cancer detection study
The Prostate2001Vol. 47(2), pp. 111–117
Citations Over TimeTop 10% of 2001 papers
Bob Djavan, Peter Mazal, A. Zlotta, R. Wammack, V. Ravery, Mesut Remzi, Martin Susani, Andrzej Borkowski, Stefan Hruby, L Boccon-Gibod, Claude C. Schulman, Michael Marberger
Abstract
At least 10% of patients with negative prostatic biopsy results will be diagnosed with CaP on repeat biopsy. Despite differences in location and multifocality, pathological and biochemical features of cancers detected on initial and repeat biopsy are similar, suggesting similar biological behavior and thus advocating for a repeat prostate biopsy in case of a negative finding on initial biopsy. Cancers missed on initial biopsy and subsequently detected on repeat biopsy are located in a more apico-dorsal location. Repeat biopsies should thus be directed to this rather spared area in order to improve cancer detection rates.
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