Inflammation in benign prostatic hyperplasia: A 282 patients' immunohistochemical analysis
The Prostate2009Vol. 69(16), pp. 1774–1780
Citations Over TimeTop 10% of 2009 papers
G. Robert, A. Descazeaud, Nathalie Nicolaı̈ew, Stéphane Terry, Nanor Sirab, Francis Vacherot, Pascale Maillé, Yves Allory, Alexandre de la Taille
Abstract
We characterized inflammatory cells infiltrate in a large cohort of surgically treated BPH specimens. The role of inflammation in BPH development was highlighted by the strong correlation between histological inflammation, IPSS, and prostate volume. Prostate enlargement due to chronic inflammatory process may progressively conduce to BPH progression. Therefore, inflammation is a therapeutic target for BPH.
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