TMPRSS2–ERG gene fusion prevalence and class are significantly different in prostate cancer of caucasian, african‐american and japanese patients
The Prostate2010Vol. 71(5), pp. 489–497
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Cristina Magi‐Galluzzi, Toyonori Tsusuki, Paul Elson, Kelly Simmerman, Christopher J. Lafargue, Raquel Esgueva, Eric A. Klein, Mark A. Rubin, Ming Zhou
Abstract
The prevalence and class of TMPRSS2-ERG are significantly different in PCa of Caucasian, African-American, and Japanese patients. Future studies of the molecular pathways implicated in TMPRSS2-ERG gene fusion may shed light on the disparity in prevalence and mortality of PCa among different ethnic groups and help design better prevention and treatment strategies.
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