Characterization of osteoblastic and osteolytic proteins in prostate cancer bone metastases
The Prostate2013Vol. 73(9), pp. 932–940
Citations Over TimeTop 10% of 2013 papers
Sandy Larson, Xiaotun Zhang, Ruth F. Dumpit, Ilsa M. Coleman, Bryce Lakely, Martine P. Roudier, Celestia S. Higano, Lawrence D. True, Paul H. Lange, Bruce Montgomery, Eva Corey, Peter S. Nelson, Robert L. Vessella, Colm Morrissey
Abstract
This is the first detailed analysis of bone remodeling proteins in human specimens of PCa bone metastases. Three proteins not previously shown to be involved may have a role in the PCa bone response. Furthermore, our data suggests that the relative expression of numerous, rather than a single, bone remodeling proteins determine the bone response in PCa bone metastases.
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