Expression of adenosine receptor subclasses in malignant and adjacent normal human prostate tissues
The Prostate2015Vol. 75(7), pp. 735–747
Citations Over TimeTop 11% of 2015 papers
Abstract
These results indicated for the first time, the differential mRNA expression profile and protein levels of adenosine receptors in the human prostate cancer. Interestingly, the A2B adenosine receptor followed by A3 is highly expressed in prostate tumor samples in comparison with the adjacent normal tissues. The findings support the possible key role of A2B adenosine receptor in promoting cancer cell growth and suggest that A2B may be a novel target for prostate cancer treatment.
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