Design, synthesis, antiviral bioactivity and three‐dimensional quantitative structure–activity relationship study of novel ferulic acid ester derivatives containing quinazoline moiety
Pest Management Science2017Vol. 73(10), pp. 2079–2089
Citations Over TimeTop 10% of 2017 papers
Zengxue Wu, Jian Zhang, Jixiang Chen, Jianke Pan, Lei Zhao, Dengyue Liu, Awei Zhang, Jin Chen, Deyu Hu, Baoan Song
Abstract
Some of the title compounds demonstrated good antiviral activities. Three-dimensional quantitative structure-activity relationship models revealed that the antiviral activities depend on steric and electrostatic properties. These results could provide significant structural insights for the design of highly active ferulic acid derivatives. © 2017 Society of Chemical Industry.
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