Anti‐inflammatory effect of Solanum lycocarpum fruits
Phytotherapy Research2003Vol. 17(8), pp. 892–896
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GILDEANNI IASMIM ALVES VIEIRA, Patrı́cia Maria Ferreira, Lécia G. de Matos, Eduardo Campos Ferreira, Wildener Monteiro Rodovalho, Pedro Henrique Ferri, Heleno Dias Ferreira, Élson Alves Costa
Abstract
The croton oil-induced mouse ear oedema test, acetic acid-induced abdominal writhing, and carrageenan-induced peritonitis were used to study the anti-inflammatory effects of the crude ethanol extract and its alkaloid fraction from Solanum lycocarpum fruits. The alkaloid fraction induced a dose-dependent reduction in ear oedema formation and leukocyte migration, suggesting that S. lycocarpum fruits may contain steroidal alkaloids accounting for the anti-inflammatory effect of the crude ethanol extract.
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