Improved low‐energy electron injection systems for high rate electron capture dissociation in Fourier transform ion cyclotron resonance mass spectrometry
Rapid Communications in Mass Spectrometry2001Vol. 15(19), pp. 1849–1854
Citations Over TimeTop 10% of 2001 papers
Yury O. Tsybin, P. Håkansson, Bogdan Budnik, Kim F. Haselmann, Frank Kjeldsen, Mikhail V. Gorshkov, Roman A. Zubarev
Abstract
New low-energy electron injection systems based on indirectly heated dispenser cathodes facilitate electron capture dissociation (ECD) in Fourier transform ion cyclotron resonance (FTICR) mass spectrometry. In this joint report, details are presented of the design and performance of these systems on two commercial FTICR instruments, 9.4 T Bruker BioAPEX in Uppsala and 4.7 T IonSpec Ultima in Odense. New results include obtaining meaningful one-scan MS/MS data for isolated precursor ions with millisecond irradiation times. The ECD rate improvement is not only due to the larger total electron current, but the larger emitting area as well.
Related Papers
- → 2D FT-ICR MS of Calmodulin: A Top-Down and Bottom-Up Approach(2016)39 cited
- → A method to generate phase continuity in two-dimensional Fourier transform ion cyclotron resonance mass spectrometry(1989)31 cited
- → Peptide and protein characterization by high‐rate electron capture dissociation Fourier transform ion cyclotron resonance mass spectrometry(2004)41 cited
- Ion Structure and Energetics in the Gas Phase Characterized Using Fourier Transform Ion Cyclotron Resonance Mass Spectrometry(2014)
- Advanced applications of high performance Fourier transform ion cyclotron resonance mass spectrometry(2014)