The host response to allogeneic and xenogeneic biological scaffold materials
Citations Over TimeTop 10% of 2014 papers
Abstract
The clinical use of biological scaffold materials has become commonplace. Such scaffolds are composed of extracellular matrix (ECM), or components of ECM, derived from allogeneic or xenogeneic tissues. Such scaffold materials vary widely in their source tissue, processing methods and sterilization methods. The success or failure of an ECM scaffold for a given application is dependent on the host response following implantation; a response that is largely mediated by the innate immune system and which is influenced by a numerous factors, including the processing methods used in the preparation of biological scaffolds. The present paper reviews various aspects of the host response to biological scaffolds and factors that affect this response. In addition, some of the logistical, regulatory and reconstructive implications associated with the use of biological scaffolds are discussed.
Related Papers
- → Nanofibrous Scaffold Engineering Using Electrospinning(2007)26 cited
- → 3D bioprinting of tissue engineering scaffold for cell culture(2020)8 cited
- Research Progress in Scaffold Materials of Skin Tissue Engineering and Its Preparation Methods(2010)
- → The Potential Matrix and Reinforcement Materials for the Preparation of the Scaffolds Reinforced by Fibers or Tubes for Tissue Repair(2017)
- Regenerative Medicine: A Scaffold Therapy in Heart Regeneration Through Tissue Engineering.(2021)