Alzheimer's disease as an autoimmune disorder of innate immunity endogenously modulated by tryptophan metabolites
Alzheimer s & Dementia Translational Research & Clinical Interventions2022Vol. 8(1), pp. e12283–e12283
Citations Over TimeTop 10% of 2022 papers
Felix Meier‐Stephenson, Vanessa Meier‐Stephenson, Michael D. Carter, Autumn Meek, Yanfei Wang, Luzhe Pan, Qiangwei Chen, Sheila Jacobo, Fan Wu, Erhu Lu, Gordon A. Simms, Laural Fisher, Alaina J. McGrath, Virgil Fermo, Christopher Barden, Harman D.S. Clair, Todd N. Galloway, Arun A. Yadav, Valérie Campágna‐Slater, Mark Hadden, Mark A. Reed, Marcia Taylor, Brendan Kelly, Elena Diez‐Cecilia, Igri Kolaj, Clarissa Santos, S. Imindu Liyanage, Braden Sweeting, Paul M. Stafford, Robert T.M. Boudreau, G. Andrew Reid, Ryan S. Noyce, Leanne M Stevens, Agnieszka Staniszewski, Hong Zhang, M. R. V. S. Murty, Pascale Lemaire, Solenne Chardonnet, Christopher D. Richardson, Valérie Gabelica, Edwin De Pauw, Richard E. Brown, Sultan Darvesh, Ottavio Arancio, Donald F. Weaver
Abstract
Conceptualizing AD as an autoimmune disease, identifying endogenous regulators of this autoimmunity, and designing small molecule drug-like analogues of these endogenous regulators represents a novel therapeutic approach for AD.
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