Genetic and multi‐omic risk assessment of Alzheimer's disease implicates core associated biological domains
Alzheimer s & Dementia Translational Research & Clinical Interventions2024Vol. 10(2), pp. e12461–e12461
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Gregory A. Cary, Jesse C. Wiley, Jake Gockley, Stephen Keegan, Sai Sruthi Amirtha Ganesh, Laura Heath, Robert R. Butler, Lara M. Mangravite, Benjamin A. Logsdon, Frank M. Longo, Allan I. Levey, Anna K Greenwood, Gregory W. Carter
Abstract
This provides an objective methodology to localize risk within specific biological endophenotypes and drill down into the most significantly associated sets of GO terms and annotated genes for potential therapeutic targets.
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