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Risk factor profiles and cognitive function in older adults: the Brain Health Support Program Study

Alzheimer s & Dementia Translational Research & Clinical Interventions2025Vol. 11(4), pp. e70173–e70173

Caroline Duchaine, Manuel Montero‐Odasso, Haakon B. Nygaard, Paul Brewster, Diane M. Jacobs, Nicole D. Anderson, Penelope Slack, J. Durant, Jody‐Lynn Lupo, Howard Chertkow, Howard Feldman, Sylvie Belleville

Abstract

This study evaluated risk profiles using a broad range of modifiable risk factors.This is the first study to analyze such profiles in a Canadian population, stratified by sex.Risk profiles differed by sex, especially for the cognitive engagement risk factor.In men, lower cognitive engagement profile was associated with poorer cognition.