Sterol metabolism in the nematodePanagrellus redivivus
Abstract
Abstract Panagrellus redivivus was propagated in media containing three structurally different sterols: 7‐dehydrocholesterol, campesterol or stigmastanol. Nematodes propagated with 7‐dehydrocholesterol contained mostly lathosterol and 7‐dehydrocholesterol. Nematodes propagated with campesterol contained mostly cholesterol and cholestanol. Nematodes propagated with stigmastanol contained mostly cholestanol. The sterol ester fraction was enriched with 4α‐methylsterols and contained the same sterols as the free sterol fraction except for nematodes propagated with 7‐dehydrocholesterol, where no dietary sterol was found in the ester fraction. P. redivivus is capable of reducing the Δ 5 ‐bond, C−24 dealkylation and methylating the sterol nucleus at C−4.
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