Ewing's sarcoma can express bone morphogenetic protein

Abstract

Paraffin sections from 6 cases of Ewing's sarcoma were immunostained by ABC method using BMP—McAb for investigating the existence of BMP in Ewing's sarcoma. All cases were positive. The result was coincided with human tumor transplants in athymic nude mouse by Bauer. It is shown that Ewing's sarcoma can express BMP. So we support the hypothesis that Ewing's sarcoma originates from primitive multipotential cells and can pluripotentially differentiate.

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